Antibacterial Activity Test of NADES (Natural Deep Eutectic Solvents) Extract of Mangkokan Leaves (Polyscias Scutellaria) Against Escherichia Coli and Staphylococcus Aureus Bacteria
DOI:
https://doi.org/10.55927/fjsr.v4i5.288Keywords:
Mangkokan (Poliyscias Scutellaria), NADES, Total Flavonoids, Antibacterial, Escherichia Coli, Staphylococcus AureusAbstract
Infection is a disease condition caused by microorganisms that grow in the body. These microorganisms can be single-celled or multicellular organisms, such as bacteria, fungi, parasites, and viruses. One of the plants that has quite promising potential is the mangkokan plant (Polyscias scutellaria). The benefits of the mangkokan plant include facilitating the digestive system, preventing hair loss, treating wounds, antibacterial, anti-inflammatory, facilitating blood circulation, preventing the appearance of symptoms of anemia and body antioxidants. This study aims to determine the total flavonoid levels and antibacterial activity of the NADES extract of mangkokan leaves (Polyscias scutellaria) against Escherichia coli and Staphylococcus aureus. The method used is the disc diffusion method. Antibacterial activity testing was carried out using concentrations of 2000 μg/disk, 4000 μg/disk, 6000 μg/disk, 8000 μg/disk using positive control chloramphenicol 30 μg/disk and negative control DMSO 1000 μg/disk. The total flavonoid content of the NADES extract of mangkokan leaves was 4.944 mgEQ/gSimplisia. NADES extract of mangkokan leaves (Polyyscias scutellaria) has antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria
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